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Exosome-associated TERRA stimulates inflammatory cytokines. (A) Experiments described in Fig. 5B where sucrose fractions from LCL exosomes were used to treat PBMCs and then assayed for induction of cytokine gene transcription, including mRNA for IL1B, MCP1, MMP1, IFNα, and IFNβ1. (B) Experiments described in Fig. 5 C–E include addition cytokine genes IL1B, MCP1, MMP1, IFNα, and IFNβ1.
