Table 1.

Animal characteristics and echocardiographic variables

	Sham	CHF
Infarct area (%)	-	25 ± 2
Body weight (initial, g)	254 ± 6	258 ± 4
Body weight (final, g)	415 ± 4	427 ± 5
LV wt/TL (mg/mm)	18 ± 0.6	21 ± 0.6*
RV wt/TL (mg/mm)	4.0 ± 0.2	5.1 ± 0.2*
Lung wt/TL (mg/mm)	26 ± 0.5	27 ± 0.7
LVEDD (mm)	7.6 ± 0.1	8.6 ± 0.2*
LVESD (mm)	4.2 ± 0.1	5.9 ± 0.1*
FS (%)	44 ± 1	32 ± 1*
LVPWThD (mm)	1.59 ± 0.03	1.40 ± 0.04*
LVPWThS (mm)	2.57 ± 0.05	2.25 ± 0.07
LVPWSV (mm/s)	35 ± 1	29 ± 1*
HR (beats/min)	382 ± 5	361 ± 6*

LV, left ventricle; RV, right ventricle; TL, tibial length; LVEDD, LV end-diastolic diameter; LVESD, LV end-systolic diameter; LVPWTh, LV posterior wall thickness during diastole (D) and systole (S); LVPWSV, posterior wall shortening velocity; FS, fractional shortening; HR, heart rate.

^*P < 0.05 by t-test for Sham (n = 18) vs. CHF (n = 22).