Table 1.
Sensitivity of Nasopharyngeal Wash and Nasopharyngeal Flocked Swab with consensus positive as the gold standard, by virus, among children < 3 years hospitalized at the Yukon-Kuskokwim Delta Regional Hospital, Alaska, October, 2005–September 2007.
| Virus | Consensus positive (% of total) (denominator = 314) | Wash positive |
Flocked swab positive |
P-value** | ||||
|---|---|---|---|---|---|---|---|---|
| # Positive (% of total) | Sensitivity | 95% CI of Sensitivity | # positive (% of total) | Sensitivity | 95% CI of Sensitivity | |||
| Group 1 viruses* | ||||||||
| Respiratory syncytial virus | 83 (26%) | 78 (25%) | 94% | (86%, 98%) | 69 (22%) | 83% | (73%, 90%) | 0.069 |
| Parainfluenza virus | 56 (18%)*** | 49 (16%) | 88% | (75%, 94%) | 48 (15%) | 86% | (73%, 93%) | 1.0 |
| Metapneumovirus | 46 (15%) | 43 (14%) | 93% | (81%, 98%) | 38 (12%) | 83% | (68%, 92%) | 0.227 |
| Influenza A and B | 18 (6%) | 16 (5%) | 89% | (64%, 98%) | 16 (5%) | 89% | (64%, 98%) | 1.0 |
| Any Group 1 Virus* | 152 (53%) | 141 (49%) | 93% | (87%, 96%) | 136 (47%) | 89% | (83%, 94%) | 0.442 |
| Group 2 viruses | ||||||||
| Rhinovirus | 142 (45%)*** | 126 (40%) | 89% | (82%, 93%) | 118 (38%) | 83% | (76%, 89%) | 0.268 |
| Adenovirus | 105 (37%)*** | 95 (34%) | 90% | (83%, 95%) | 37 (13%) | 35% | (26%, 45%) | <0.001 |
| Coronavirus | 19 (6%)*** | 13 (4%) | 69% | (43%, 86%) | 15 (5%) | 79% | (54%, 93%) | 0.754 |
*
Any Group 1 omits episodes where the child is positive for more than one Group 1 virus (n = 288).
**
p-Value compares sensitivity of wash and flocked swab.
***
Denominator = 313.