Table 1.
Baseline clinical and laboratory characteristics according to thrombus burden.
| Variable | Low thrombus burden (n=299) | High thrombus burden (n=481) | P value |
|---|---|---|---|
| Age, years | 55.4±10.8 | 57.1±11 | .033 |
| Sex, male% | 43.5 | 49.5 | .105 |
| Diabetes,% | 23.7 | 30.4 | .049 |
| Hypertension,% | 42.5 | 43.2 | .882 |
| Smoking,% | 42.1 | 44.9 | .459 |
| Dyslipidemia,% | 43.5 | 48 | .237 |
| Previous history of CAD,% | 11 | 14 | .297 |
| Family history of CAD | 37.4 | 43.2 | .116 |
| Pain-balloon time, min | 220±121 | 280±502 | .042 |
| Door-balloon time, min | 30.8±10.9 | 30.4±10.2 | .623 |
| Killip status (≥II) | 9 | 13.3 | .085 |
| Heart rate, /min | 76.5±16 | 74.7±16 | .145 |
| Hemoglobin, g/dL | 13.3±1.4 | 13.9±1.3 | .732 |
| White blood cell count ×103/μL | 9.2±2.5 | 9.7±2.5 | .013 |
| Platelet count, ×103/μL | 216±76 | 218±78 | .734 |
| Baseline troponin I, mg/L | 2.1±1.5 | 2.3±1.5 | .047 |
| Baseline CK-MB, IU/L | 35±13.7 | 37.1±15.1 | .048 |
| LDL cholesterol, mg/dL | 150±32 | 155±26 | .188 |
| HDL cholesterol, mg/dL | 29±14 | 28±11 | .913 |
| Triglyceride, mg/dL | 188±91 | 201±102 | .061 |
| EF,% | 48±9.8 | 47.7±8.1 | .595 |
| Previous medications,% | |||
| Aspirin | 14.7 | 13.1 | .523 |
| Statin | 16.7 | 17.0 | .922 |
| ACE inhibitors/ARB | 26.8 | 29.7 | .415 |
| β-blocker | 8.7 | 6.0 | .195 |
| Clopidogrel | 1 | 2.7 | .124 |
| CCB | 16.7 | 17.9 | .699 |
| Antidiabetic medications | 9.6 | 7.8 | .104 |
CAD – coronary artery disease; LDL – low-density lipoprotein; HDL – high-density lipoprotein; ACE – angiotensin converting enzyme; ARB – angiotensin receptor blocker; CCB – calcium channel blocker; OAD – oral antidiabetic drug. The normal cut-off value of troponin in our laboratory <0.04 mg/L.