Table 3.

MRI estimates

	% BOLD Signal Change
Functional Regions	BD Group	HC Group
L DLPFC (encode)	0.42 (0.06)	0.49 (0.04)
R DLPFC (encode)	0.05 (0.04)	0.24 (0.04)
L DLPFC (maintenance)	0.13 (0.03)	0.14 (0.03)
R DLPFC (maintenance)	0.09 (0.03)	0.05 (0.03)
L Supramarginal Gyrus (encode)	0.11 (0.04)	0.23 (0.05)
L Supramarginal Gyrus (maintenance)	0.08 (0.02)	0.09 (0.02)
R Supramarginal Gyrus (maintenance)	−0.01 (0.02)*	0.04 (0.02)
	Fractional Anisotropy
Structural Regions	BD Group	HC Group
Corpus Callosum - Body	0.58 (0.009)	0.59 (0.010)
Corpus Callosum - Genu	0.61 (0.007)	0.62 (0.009)
Corpus Callosum - Splenium	0.69 (0.007)	0.70 (0.006)
L Uncinate Fasciculus	0.43 (0.008)	0.42 (0.008)
R Uncinate Fasciculus	0.46 (0.008)	0.47 (0.008)
L Superior Longitudinal Fasciculus	0.46 (0.004)	0.46 (0.005)
R Superior Longitudinal Fasciculus	0.45 (0.004)	0.46 (0.005)

Data reflect mean and standard errors in parentheses for functional magnetic resonance imaging percent change in BOLD signal from baseline and diffusion tensor imaging fractional anisotropy. BOLD: blood oxygen level dependent; L: left; R: right; encode: working memory task encode interval; maintenance: working memory task maintenance interval; BD: bipolar disorder patients; HC: healthy comparison participants.

^*No significant cluster found for bipolar patients: values reflect patient data from the HC-derived cluster.