Example of spatiotemporal trajectories during forward deflection of whisker group 2 (D2, C2, D3 and C3). A) The trajectories have been computed with time sequenced images, using a particle filter approach, resulting in a B) set of 3D curves of activity propagation, color-coded with timing of activation over milliseconds. C) The surface (left) and coronal (right) views reveal that activity starts in layer IV, propagates into supra- and infragranular layers within the stimulated barrels, and then spreads to adjacent whisker barrel rows predominantly through layers II/III.