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. 2015 Oct;56(5):447–459. doi: 10.3325/cmj.2015.56.447

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Copyright © 2015 by the Croatian Medical Journal. All rights reserved.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Relative expression of Adh1 (A) and Hao1 mRNA (B) in the liver and kidneys of control (Ctr) and ethylene glycol (EG)-treated (EG) female and male rats. (A) In the liver and kidneys of control animals, the relative expression of Adh1 mRNA in females was respectively ~ 2-fold (*P = 0.028) and ~ 4.3-fold (*P < 0.001) higher than in males, and remained unaffected by EG-treatment in both sexes (vs the respective control data, P ≥ 0.127). (B) In the liver and kidneys of control animals, the relative expression of Hao1 mRNA in males was respectively ~ 3-fold (*P < 0.001) and ~ 4-fold (*P < 0.001) higher than in females, and remained unaffected by EG-treatment in both sexes (vs the respective control data, P≥0.167). Bars represent the data from 5 (liver) and 6 (kidney) animals.