Table 1.

ROI analysis for different cleaning approaches. Group comparison of average P.E. in the basal ganglia ROIs extracted from single-subject BGN maps.

	Average P.E. in the BGN		Group comparison HC vs PD		Average P.E. in the BGN		Group comparison HC vs PD
	HC (mean ± stdev)	PD (mean ± stdev)	t-value	p-value⁎	HC (mean ± stdev)	PD (mean ± stdev)	t-value	p-value⁎
	Left putamen				Right putamen
Uncleaned	23.38 ± 9.06	16.05 ± 7.36	2.739	0.01	22.61 ± 8.65	17.08 ± 7.02	2.162	0.037
Motion	19.06 ± 7.79	11.61 ± 5.29	3.444	0.001⁎	17.92 ± 6.94	12.61 ± 5.06	2.695	0.011
Standard 20	16.65 ± 6.20	10.00 ± 4.03	3.92	< 0.001⁎	16.01 ± 6.25	10.14 ± 3.82	3.493	0.002⁎
OPDC 5	15.27 ± 5.57	10.15 ± 3.33	3.441	0.002⁎	15.18 ± 6.29	10.15 ± 3.42	3.062	0.005⁎
OPDC 10	14.53 ± 5.44	9.62 ± 3.28	3.366	0.002⁎	14.19 ± 5.53	9.65 ± 3.40	3.046	0.005⁎
Manual	11.73 ± 5.10	7.54 ± 2.88	3.116	0.004⁎	11.36 ± 4.71	7.69 ± 2.26	3.06	0.005⁎
	Left caudate				Right caudate
Uncleaned	20.82 ± 7.85	17.81 ± 6.92	1.252	0.219	19.68 ± 10.07	15.88 ± 8.51	1.258	0.216
Motion	16.73 ± 7.22	11.96 ± 5.18	2.341	0.025	15.73 ± 8.48	10.31 ± 5.98	2.277	0.029
Standard 20	14.70 ± 6.86	9.56 ± 4.22	2.782	0.009	14.43 ± 7.61	7.60 ± 4.46	3.371	0.002⁎
OPDC 5	13.90 ± 6.68	10.25 ± 3.91	2.052	0.049	13.35 ± 6.96	8.17 ± 4.33	2.755	0.009
OPDC 10	13.27 ± 6.65	9.74 ± 3.54	2.041	0.051	12.58 ± 7.18	7.85 ± 3.98	2.513	0.017
Manual	10.87 ± 5.37	7.82 ± 2.57	2.229	0.035	10.30 ± 5.47	6.46 ± 3.30	2.625	0.013
	Left pallidum				Right pallidum
Uncleaned	13.10 ± 7.27	7.48 ± 5.73	2.646	0.012	12.75 ± 8.76	8.47 ± 4.64	1.882	0.068
Motion	10.49 ± 5.54	5.42 ± 4.85	3.001	0.005⁎	10.51 ± 6.81	6.05 ± 3.78	2.494	0.017
Standard 20	8.68 ± 4.55	4.79 ± 2.76	3.192	0.003⁎	8.67 ± 6.41	4.66 ± 2.96	2.478	0.02
OPDC 5	7.37 ± 5.04	5.01 ± 2.73	1.798	0.081	7.86 ± 6.29	4.67 ± 2.88	2.008	0.052
OPDC 10	7.18 ± 5.56	4.63 ± 2.81	1.783	0.083	7.28 ± 4.93	4.20 ± 2.85	2.358	0.024
Manual	5.35 ± 4.70	3.74 ± 2.60	1.301	0.201	5.07 ± 3.46	3.34 ± 2.21	1.831	0.075

^⁎Significant after correction for multiple comparisons across 6 structures.