Fig. 6.

Coincident location of IIS and reconstructed impedance changes. (A–C) Smoothed ECoG map (left column) and reconstructed impedance changes (middle and right columns) for three rats. The orientation of the rasters is the same as that of the electrode maps in Fig. 3. ECoG maps are shown at the time of the IIS peak, and impedance changes are shown at 1 mm depth and at the time of maximum change before the IIS peak (middle column; time shown in inset) or at 500 ms after the IIS peak (right column). Seizure models shown: 4-AP (A; same rat as in Fig. 5), picrotoxin (B) and penicillin (C). (D) Distance in mm between the centres-of-mass of the negative ECoG deflections and the impedance changes for all 8 rats.