Table 1.

Summary results for the IIS-triggered dZ signals in all rats measured across all current injection configurations. The electrographic patterns of the IIS's were stable over the duration of the recordings. Fast dZ: component of dZ signal occurring around the time of the IIS peak; Slow dZ: component of dZ signal occurring after IIS; Corr: correlation between peak amplitudes of fast and slow dZ components; n IIS: number of interictal spikes used in the analysis; max. (%) and median (%): maximum and median peak amplitude in dZ signal component; t_neg (ms): median time of negative peak in dZ signal; t_sig (ms): median time when dZ signal first turns positive; t_pos (ms): median time of positive peak in dZ signal; and r: Pearson correlation coefficient (all p < 0.001).

			Fast dZ			Slow dZ				Corr.
Rat #	n IIS	Max. (%)	Median (%)	tneg (ms)	Max. (%)	Median (%)	tsig (ms)	tpos (ms)	r
4-AP	1	596	− 0.3	− 0.04	− 10.0	0.69	0.14	19	334	− 0.59
2	148	− 0.26	− 0.07	− 7.2	1.27	0.19	39	713	− 0.84
Picrotoxin	1	630	− 0.64	− 0.12	− 10.8	1.62	0.28	58	734	− 0.42
2	821	− 0.42	− 0.1	− 6.4	0.61	0.14	32	406	− 0.45
3	828	− 0.26	− 0.07	− 12.1	0.93	0.21	117	766	− 0.87
Penicillin	1	279	− 0.93	− 0.13	− 0.56	2.34	0.29	46	930	− 0.46
2	292	− 0.47	− 0.17	− 1.17	1.55	0.43	62	699	− 0.41
3	1128	− 0.47	− 0.12	1.82	1.07	0.17	46	537	− 0.52