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. 2015 Nov 18;10:7129–7143. doi: 10.2147/IJN.S92179

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© 2015 Tang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Ultrastructure of SMMC-7721 cells (observed by TEM).

Notes: Sections from the blank control group (A); gene transfection-alone group (B); thermotherapy-alone group (C); and combined therapy group (D and E) are shown. TEM examination revealed that the necrotic areas in C and D were much larger than the intrinsic necrosis of the tumor shown in A and B. The black arrows indicate the magnetic nanoparticles. Magnification: A–C ×6,000; D ×12,000; E ×30,000.

Abbreviation: TEM, transmission electron microscopy.