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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Clin Res Hepatol Gastroenterol. 2015 Jul 16;39(0 1):S24–S28. doi: 10.1016/j.clinre.2015.05.016

Figure 1.

Figure 1

A schematic diagram of Notch1-dependent upregulation of PDP1, which dephosphorylates and activates PDH-E1α to enhance glucose flux to mitochondrial TCA cycle metabolism.