Table 2.

Characteristics of cumulative neuropsychiatric syndromes incorporating attribution models A and B over the study period in SLE patients.

	NP events (%) regardless of attribution		NP events due to SLE (model A)	NP events due to SLE (Model B)	NP events due to non-SLE causes
Headache	657	(48.4)	0	0	657
Mood disorders	213	(15.7)	33	73	140
Seizure disorder	91	(6.7)	59	78	13
Anxiety disorder	70	(5.2)	0	0	70
Cerebrovascular disease	70	(5.2)	28	68	2
Cognitive dysfunction	61	(4.5)	12	35	26
Polyneuropathy	44	(3.2)	16	20	24
Acute confusional state	33	(2.4)	16	26	7
Mononeuropathy	27	(2.0)	14	27	0
Psychosis	23	(1.7)	10	22	1
Cranial neuropathy	24	(1.8)	20	20	4
Movement disorder	11	(0.8)	4	8	3
Myelopathy	13	(1.0)	7	12	1
Aseptic meningitis	8	(0.6)	5	5	3
Demyelinating syndrome	6	(0.4)	1	6	0
Autonomic disorder	2	(0.2)	2	2	0
Plexopathy	1	(0.1)	0	0	1
Guillain-Barre syndrome	2	(0.2)	2	2	0
Myasthenia gravis	2	(0.2)	0	2	0
Total		1358	229	406	952
% among 1358 NP events			16.9	29.9	70.1

^*The attribution of neuropsychiatric (NP) events to SLE was determined using two attribution models:

Attribution Model A: NP events which had their onset within the enrollment window and had no “exclusions” or “associations” and were not one of the NP events identified by Ainiala (12) were attributed to SLE.

Attribution Model B: NP events which had their onset within 10 years of the diagnosis of SLE and were still present within the enrollment window and had no “exclusions” and were not one of the NP events identified by Ainiala (12) were attributed to SLE.