FIGURE 1:

High-phosphate diet induces media calcification in the abdominal aorta, but not in the thoracic aorta. DBA/2 mice fed with a high-phosphate diet for 14 days developed no histopathological signs of arterial calcifications in the thoracic aorta (A and C), whereas there was a clear phenotype of media calcification in the abdominal aorta (B and D). The histopathological evaluation was performed with Alizarin Red stainings. # denotes the aortic lumen. The scale bar measures 200 µm (A, B) and 50 µm (C, D).