Table 5.

Methods to improve drug dissolution.

Enhancing Drug Solubility	Enhancing Dissolution Kinetics
Using surfactant micelles	Selecting appropriate polymorph
Using polymer micelles	Making amorphous forms (solid dispersions)
Using hydrotropic agents	Reducing particle size (nanocrystals)
Using complexing agents	Adding surfactant for better wetting
Using cosolvents
Using self-emulsifying systems
Controlling pH