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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Transl Res. 2015 Jun 24;166(6):706–720.e11. doi: 10.1016/j.trsl.2015.06.008

Fig. 1. Pelvic muscle and mucosa pressure pain is enhanced in women with VBD and VBD+IBS, while remote bodily muscle pain and thermal windup is enhanced only in women with VBD+IBS.

Fig. 1

Women with VBD or VBD+IBS reported greater pain intensity and decreased pain thresholds in the pelvic muscle (A–B) and mucosa (C–D). Women with VBD+IBS demonstrated a trend towards decreased pressure pain thresholds in the trapezius (E) and temporomandibular joint (F) as compared to HC and VBD. (G) For the thermal data, there was a significant interaction between study group and stimulus sequence, although not between study group and the square of stimulus sequence. VBD+IBS women exhibit the greatest degree of pain in response to the windup thermal heat assay. Data are Mean ± SEM. *p<0.05, ***p<0.001, ****p<0.0001 compared to HC; †p<0.05 as compared to HC and VBD.