Fig. 3. miRNA expression signatures are altered in women with VBD and VBD+IBS.
Compared to HC, women with VBD exhibit significant downregulation of 7 and upregulation of 3 miRNAs (A), while women with VBD+IBS exhibit significant downregulation of 6 and upregulation of 5 miRNAs (B). Red dots represent downregulated miRNAs and blue dots represent upregulated miRNAs compared to HC. Four miRNAs are dysregulated in both VBD and VBD+IBS women. Dysregulated miRNAs are listed with fold change and p values (C).