Table 1.

Summary of AHA guidelines regarding the follow-up of patients with Kawasaki disease, starting at 1 year

Risk level	Diagnostic testing	Interval	Invasive testing
No CAA	Cardiovascular risk assessment	5 years	None
Transient CAA^a	Cardiovascular risk assessment	3–5 years	None
Small-medium CAA (>3 mm but <6 mm, z-score 3–7)	Cardiovascular risk assessment Echocardiogram + ECG	1 year 1 year	Invasive CAG if non-invasive test suggests ischemia
Small-medium CAA (>3 mm but <6 mm, z-score 3–7)	Stress test with MPI	2 years	Invasive CAG if non-invasive test suggests ischemia
Large CAA (≥6 mm) or Multiple or complex CAA in 1 artery	Echocardiogram + ECG	one half year	Invasive CAG after 6–12 months and if any test or clinical finding suggests ischemia
Large CAA (≥6 mm) or Multiple or complex CAA in 1 artery	Stress test with MPI	1 year
Coronary artery obstruction	Echocardiogram + ECG	one half year	Invasive CAG for therapeutic options and if new onset or worsening myocardial ischemia is suggested
Coronary artery obstruction	Stress test with MPI	1 year

From: Newburger et al., Circulation. 2004;110(17):2747–71⁸

CAG conventional angiography, MPI myocardial perfusion imaging

^aDisappearing within 6–8 weeks after the onset of Kawasaki disease