Figure 1.

Q-RPA data demonstrating down-regulation of ASBT and t-ASBT message following TCA feeding and up-regulation of their expression following CY feeding in cholangiocytes. Bar graphs demonstrating ASBT and t-ASBT mRNA expression, in which 40 μg total cellular RNA isolated from cholangiocytes obtained from rats fed regular chow (C), 1% TCA or 5% CY incorporated diets were used. Densitometric values shown here are expressed as mean ± SE and represent 3 feeding studies in which 30 rats in total were analyzed per group (^aP < 0.05).