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Intracellular DNR concentrations in cells treated with antisense oligonucleotids. The concentration of each AS-ODN is 0.5 mmol/L and the treatment time is 72 h. Data are the mean ± standard deviation of three independent experiments. (1. SMMC7721/R; 2. SMMC7721/S; 3. SMMC7721/R treated with AS-ODN/mdr1+mrp; 4. SMMC7721/R treated with AS-ODN/mdr1; 5. SMMC7721/R treated by AS-ODN/mrp; 6. SMMC7721/R treated with AS-ODN/nonsense.)
