Table 1.
Clinicopathologic characteristics of colorectal cancer with expression of TGFβ1 and TGFβRII
| Variables | n | TGFβ1-positive n (%) | TGFβRII-positive n (%) | |
| Age (yrs) | ≥ 50 | 60 | 24 (40.0) | 30 (50.0) |
| < 50 | 38 | 13 (34.2) | 16 (42.1) | |
| Sex | Male | 53 | 20 (41.5) | 25 (53.7) |
| Female | 45 | 17 (31.0) | 21 (37.9) | |
| Tumor size | < 5 cm | 56 | 21 (37.5) | 24 (42.9) |
| ≥ 5 cm | 42 | 16 (38.1) | 22 (52.4) | |
| Histology | ||||
| Well-diff. ade | 17 | 9 (52.9) | 11 (64.7) | |
| Mode-diff. ade | 47 | 15 (31.9) | 19 (40.4) | |
| Poor-diff. ade | 34 | 13 (38.2) | 16 (47.1) | |
| Depth of invasion | ||||
| T1-T2 | 60 | 17 (28.3) | 33 (55.0) | |
| T3-T4 | 38 | 20 (52.6)a | 13 (34.2)a | |
| Metastasis | Present | 35 | 18 (51.4) | 11 (31.4) |
| Absent | 63 | 19 (30.2)a | 35 (55.6)a | |
| Stage | A | 34 | 8 (23.5) | 23 (67.7) |
| B | 29 | 9 (31.1) | 13 (44.8) | |
| C+D | 35 | 20 (57.1)a | 10 (28.6)a | |
aP < 0.05, T1-T2 vs T3-T4, Present vs Absent, A, B vs C+D