Table 1.
HLA-DRB1 allele |
Normal control (n = 106) |
Chronic hepatitis B (n = 52) |
Acute hepatitis B (n = 30) |
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PN | AF | PN | AF | PN | AF | |
0101/0103 | 1 | 0.47 | 1 | 0.96 | 1 | 1.67 |
0301* | 12 | 5.66 | 18 | 17.31 | 6 | 10.00 |
0401/0411 | 24 | 11.32 | 13 | 12.50 | 7 | 11.67 |
0701/0702 | 11 | 5.19 | 8 | 7.69 | 4 | 6.67 |
0801/0804 | 9 | 4.25 | 6 | 5.77 | 3 | 5.00 |
0901 | 32 | 15.09 | 16 | 15.39 | 8 | 13.33 |
1001 | 2 | 0.94 | 2 | 1.92 | 1 | 1.67 |
1101/1104** | 13 | 6.13 | 1 | 0.96 | 8 | 13.33 |
1201/1202 | 34 | 16.04 | 15 | 14.42 | 8 | 13.33 |
1301/1302 | 4 | 1.89 | 1 | 0.96 | 1 | 1.67 |
1303/1304 | 1 | 0.47 | 1 | 0.96 | 1 | 1.67 |
1401, 1404 | 14 | 6.60 | 6 | 5.77 | 4 | 6.67 |
1402, 1403 | 0 | 0.00 | 0 | 0.00 | 0 | 0.00 |
1501/1502 | 34 | 16.04 | 11 | 10.58 | 5 | 8.33 |
1601/1602 | 13 | 6.13 | 2 | 1.92 | 1 | 1.67 |
Blank | 8 | 3.77 | 3 | 2.89 | 2 | 3.33 |
PN: Positive number, AF: Allele frequency. *χ2 = 12.3068, Pc = 0.0074, RR = 4.15. **χ2 = 11.9206, Pc = 0.0145, RR = 18.55.