Table 2.
Allele frequency of HLA-DQA1 in patients with chronic and acute hepatitis B and normal heathy individuals
| HLA-DQA1 allele |
Normal control (n = 106) |
Chronic hepatitis B (n = 52) |
Acute hepatitis B (n = 30) |
|||
| PN | AF | PN | AF | PN | AF | |
| 0101 | 17 | 8.02 | 9 | 8.65 | 4 | 6.67 |
| 0102 | 45 | 21.23 | 22 | 21.15 | 12 | 20.00 |
| 0103 | 9 | 4.25 | 5 | 4.81 | 2 | 3.33 |
| 0104 | 3 | 1.42 | 1 | 0.96 | 1 | 1.67 |
| 0201 | 7 | 3.30 | 3 | 2.88 | 1 | 1.67 |
| 0301* | 57 | 26.89 | 15 | 14.42 | 18 | 30.00 |
| 0302 | 1 | 0.47 | 0 | 0.00 | 0 | 0.00 |
| 0401 | 2 | 0.49 | 1 | 0.96 | 1 | 1.67 |
| 0501** | 29 | 13.68 | 27 | 25.96 | 10 | 16.67 |
| 0601 | 23 | 10.85 | 12 | 11.54 | 6 | 10.00 |
| Blank | 19 | 8.96 | 9 | 8.65 | 5 | 8.33 |
PN: Positive number, AF: Allele frequency. *χ2 = 7.6781, Pc = 0.0388, RR = 3.70. **χ2 = 9.2002, Pc = 0.0157, RR = 2.87.