Table 3.
Allele frequency of HLA-DQB1 in patients with chronic and acute hepatitis B and normal heathy individuals
| HLA-DQB1 allele |
Normal control (n = 106) |
Chronic hepatitis B (n = 52) |
Acute hepatitis B (n = 30) |
|||
| PN | AF | PN | AF | PN | AF | |
| 0201 | 23 | 10.85 | 10 | 9.62 | 6 | 10.00 |
| 0301* | 40 | 18.87 | 37 | 35.58 | 16 | 26.67 |
| 0302 | 14 | 6.61 | 6 | 5.77 | 3 | 5.00 |
| 0303 | 35 | 16.51 | 15 | 14.42 | 10 | 16.67 |
| 0401 | 11 | 5.19 | 5 | 4.81 | 3 | 5.00 |
| 0402 | 2 | 0.94 | 1 | 0.96 | 1 | 1.67 |
| 0501 | 9 | 4.25 | 3 | 2.88 | 2 | 3.33 |
| 0502 | 20 | 9.43 | 7 | 6.73 | 3 | 5.00 |
| 0503 | 6 | 2.83 | 2 | 1.92 | 1 | 1.67 |
| 0601 | 20 | 9.43 | 7 | 6.73 | 7 | 11.67 |
| 0602 | 12 | 5.66 | 4 | 3.85 | 3 | 5.00 |
| 0603 | 5 | 2.36 | 2 | 1.92 | 1 | 1.67 |
| 0604 | 7 | 3.30 | 2 | 1.92 | 2 | 3.33 |
| Blank | 8 | 3.77 | 3 | 2.89 | 2 | 3.33 |
PN: Positive number, AF: Allele frequency. χ2 = 15.5938, Pc = 0.0075, RR = 4.07.