Table 4.
Prevalence among blood donors with normal and abnormal ALT according to the six definitions
| Subjects | Method 1: | Method 2: | Method 3: | Method 4: 95th | Method 5: 95th | Method 6: 95th |
| 95th percentile | 95th percentile | 40 IU/L for | percentile of | percentile of | percentile of ALT | |
| of ALT distribution | of ALT distribution | both male | ALT distribution | ALT distribution | distribution stratified | |
| without stratification | stratified according | and female | stratified according | stratified according | according to BMI | |
| to sex | to BMI (< 27.1) | to BMI (< 25) | (< 25) and sex | |||
| Males | 1451 | 1451 | 1451 | 1451 | 1451 | 1451 |
| Threshold | 40 | 45 | 40 | 39 for BMI ≥ 27.1 | 39 for BMI < 25 | 40 for BMI < 25 |
| 41/721 | 20/391 | 16/391 | ||||
| 45 for BMI > 27.1 | 43 for BMI ≥ 25 | 46 for BMI ≥ 25 | ||||
| 40/730 | 65/1060 | 48/1060 | ||||
| Normal (%) | 1363 (94%) | 1378 (95%) | 1363 (94%) | 1370 (94.5%) | 1366 (94.1%) | 1387 (95.6%) |
| Abnormal (%) | 88 (6%) | 73 (5%) | 88 (6%) | 81 (5.5%) | 85 (5.9%) | 64 (4.4%) |
| Females | 488 | 488 | 488 | 488 | 488 | 488 |
| Threshold | 40 | 34 | 40 | 39 for BMI ≥ 27.1 | 39 for BMI < 25 | 34 for BMI < 25 |
| 6/249 | 4/172 | 8/172 | ||||
| 45 for BMI > 27.1 | 43 for BMI ≥ 25 | 34 for BMI ≥ 25 | ||||
| 2/239 | 2/316 | 15/316 | ||||
| Normal (%) | 481 (98.6%) | 464 (95%) | 481 (98.6%) | 480 (98.4%) | 482 (98.8%) | 465 (95.3%) |
| Abnormal (%) | 7 (1.4%) | 24 (5%) | 7 (1.4%) | 8 (1. 6%) | 6 (1.2%) | 23 (4.7%) |
| All donors | 1939 | 1939 | 1939 | 1939 | 1939 | 1939 |
| Threshold | 40 | 45 for female | 40 | 39 for BMI ≥ 27.1 | 39 for BMI < 25 | Male: 40 for BMI < 25 |
| 34 for male | 45 for BMI > 27.1 | 43 for BMI ≥ 25 | 46 for BMI ≥ 25 | |||
| Female: 34 for BMI < 25 | ||||||
| 34 for BMI ≥ 25 |