Table 2.
Treatment | Incidencen (%) | Total no.tumors | Adenoma No (%) | Carcinoma in situ No (%) | Carcinoma No (%) | Multiplicityb No. | Tumor volumemm3 |
Duke’s stagec |
||
A | B | C | ||||||||
DMH + lactic acid | 9 (90) | 28 | 12 (43) | 8 (28.5) | 8 (28.5) | 3.11 ± 2.00 | 1.64 ± 1.92 | 0 | 2 | 1 |
DMH | 10 (100) | 40 | 27 (67.5) | 3 (7.5) | 10 (25) | 4.00 ± 2.96 | 4.31 ± 4.56 | 0 | 0 | 3 |
a: Values are means ± SD. b: No. of tumors/tumor-bearing rat. c: No. of rats with carcinoma were allocated to one of three tumor stages.