Table 1.
Parameters | ICG-HNPCC | sHNPCC | Total | Sporadic CRC |
Sex male | 6 (50%) | 14 (33.3%) | 20 (37%) | 319 (43%) |
female | 6 (50%) | 28 (66.7%) | 34 (63.0%) | 423 (57%) |
Mean age | 39 y | 47.5 y | 45.7 y | 56 y |
tumor site colon | 9 (75.0%) | 26 (62.0%) | 35 (64.8%) | 226 (30.5%) |
rectum | 3 (25.0%) | 16 (38.0%) | 19 (35.2%) | 516 (69.5%) |
Dukes' stage A+B | 7 (58.3%) | 34 (81.0%) | 41 (75.9%) | 347 (47.8%) |
C+D | 5 (41.7%) | 8 (19.0%) | 13 (24.1%) | 380 (52.2%) |
Differentiation high | 6 (54.5%) | 12 (30.8%) | 18 (36.0%) | 89 (15.3%) |
moderate | 5 (45.5%) | 22 (56.4%) | 27 (54.0%) | 397 (68.1%) |
poorly | 0 | 5 (12.8%) | 5 (10.0%) | 97 (16.6%) |
Pathology mucinous tumors | 1 (8.3%) | 9 (21.4%) | 10 (18.5%) | 159 (21.4%) |
Non-mucinous tumors | 11 (91.7%) | 33 (78.6%) | 44 (81.5%) | 583 (78.6%) |
Multiple CRCs | 2 (16.7%) | 6 (14.3%) | 8 (14.8%) | 25 (3.4%) |