Table 1.
Liver enzymes, serum fibrosis indicators and hepatic antioxidation (¯x ± s)
| Group | n | ALT (nkat/L) | AST (nkat/L) | HA (μg/L) | CIV (μg/L) | MDA (nmol/g) | SOD (kNU/g) |
| Males | |||||||
| Control | 10 | 31 ± 6 | 66 ± 18 | 115 ± 31 | 18 ± 5 | 3.1 ± 0.9 | 8.0 ± 1.6 |
| CCL4 | 10 | 576 ± 262a | 699 ± 241a | 530 ± 122a | 54 ± 14a | 10.5 ± 3.4a | 2.2 ± 1.1a |
| CCL4 + E | 8 | 355 ± 125c | 314 ± 179c | 232 ± 78c | 30 ± 10c | 6.6 ± 2.8c | 5.0 ± 1.6c |
| CCL4 + Tam | 8 | 884 ± 294c | 1073 ± 453c | 703 ± 187c | 69 ± 5c | ||
| Females | |||||||
| Control | 10 | 35.8 ± 7.9 | 64.5 ± 20.8 | 121 ± 26 | 17 ± 4 | 3.0 ± 0.8 | 8.7 ± 2.8 |
| CCL4 | 9 | 540 ± 252a | 631 ± 268a | 388 ± 81a | 41 ± 11a | 7.1 ± 2.1a | 4.0 ± 1.5a |
| CCL4 + Ovx | 10 | 658 ± 220 | 697 ± 240 | 586 ± 145c | 53 ± 14c | 9.1 ± 2.9c | 2.8 ± 1.0c |
| CCL4 + E | 8 | 314 ± 163c | 302 ± 153c | 267 ± 83c | 29 ± 7c | 4.7 ± 2.2c | 5.9 ± 2.0c |
| CCL4 + Ovx + E | 9 | 311 ± 146c | 321 ± 121c | 236 ± 119c | 31 ± 7c | 4.8 ± 2.3c | 6.2 ± 2.5c |
a
P < 0.05, vs control;
c
P < 0.05, vs CCL4