Table 1.
Tissue | T(post-inj)/h |
188Re-HAb18 F(ab’)2 |
|
%ID·g-1(-x ± s) | T/NT ratio | ||
Tumor | 1 | 3.01 ± 0.89 | ND |
4 | 3.94 ± 0.82 | ND | |
18 | 3.43 ± 0.28 | ND | |
24 | 1.96 ± 0.43 | ND | |
48 | 0.99 ± 0.32 | ND | |
Blood | 1 | 4.58 ± 0.63 | 0.66 |
4 | 1.83 ± 0.10 | 2.15 | |
18 | 0.21 ± 0.04 | 16.30 | |
24 | 0.18 ± 0.03 | 10.90 | |
48 | 0.05 ± 0.01 | 19.80 | |
Heart | 1 | 1.60 ± 0.38 | 1.88 |
4 | 0.80 ± 0.10 | 4.92 | |
18 | 0.36 ± 0.03 | 9.53 | |
24 | 0.30 ± 0.02 | 6.53 | |
48 | 0.21 ± 0.03 | 4.71 | |
Liver | 1 | 2.07 ± 0.40 | 1.45 |
4 | 1.57 ± 0.31 | 2.51 | |
18 | 0.77 ± 0.12 | 4.45 | |
24 | 0.66 ± 0.10 | 2.97 | |
48 | 0.47 ± 0.13 | 2.11 | |
Spleen | 1 | 1.22 ± 0.25 | 2.47 |
4 | 0.91 ± 0.22 | 4.33 | |
18 | 0.47 ± 0.07 | 7.30 | |
24 | 0.45 ± 0.08 | 4.36 | |
48 | 0.41 ± 0.10 | 2.40 | |
Lung | 1 | 1.45 ± 0.23 | 2.08 |
4 | 0.86 ± 0.29 | 4.58 | |
18 | 0.19 ± 0.04 | 18.10 | |
24 | 0.18 ± 0.04 | 10.90 | |
48 | 0.14 ± 0.05 | 7.07 | |
Kidney | 1 | 59.81 ± 14.52 | 0.05 |
4 | 47.83 ± 12.87 | 0.08 | |
18 | 18.72 ± 4.94 | 0.18 | |
24 | 15.80 ± 0.99 | 0.12 | |
48 | 7.31 ± 2.10 | 0.13 | |
Large | 1 | 1.36 ± 0.38 | 2.21 |
intestine | 4 | 0.93 ± 0.24 | 4.24 |
18 | 0.57 ± 0.06 | 6.02 | |
24 | 0.45 ± 0.00 | 4.36 | |
48 | 0.18 ± 0.03 | 5.50 | |
Small | 1 | 1.61 ± 0.43 | 1.87 |
intestine | 4 | 0.88 ± 0.29 | 4.24 |
18 | 0.33 ± 0.05 | 10.40 | |
24 | 0.29 ± 0.05 | 6.76 | |
48 | 0.13 ± 0.05 | 7.62 | |
Muscle | 1 | 0.74 ± 0.29 | 4.07 |
4 | 0.44 ± 0.12 | 8.95 | |
18 | 0.19 ± 0.08 | 18.10 | |
24 | 0.16 ± 0.06 | 12.25 | |
48 | 0.05 ± 0.02 | 19.80 | |
Bone | 1 | 1.03 ± 0.31 | 2.92 |
4 | 0.68 ± 0.12 | 5.79 | |
18 | 0.31 ± 0.09 | 11.06 | |
24 | 0.27 ± 0.02 | 7.26 | |
48 | 0.16 ± 0.02 | 6.19 |
ND: not done