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One h effect of prucalopride on intestinal motility in SD rats (-x ± s, n = 10)
| Group | GI length (cm) | Migration of activated charcoal (cm) | GI propulsion rate (%) |
| Control | 82.9 ± 12.2 | 63.8 ± 10.5 | 77.9 ± 7.5 |
| Prucalopride (1 mg/kg) | 70.9 ± 4.1 | 59.7 ± 9.5 | 84.0 ± 11.7b |
| Prucalopride (2 mg/kg) | 73.8 ± 11.7 | 57.0 ± 12.8 | 77.1 ± 11.9a |
| Cisapride (1 mg/kg) | 78.1 ± 10.7 | 52.2 ± 14.4 | 66.3 ± 13.6 |
P < 0.05,
P < 0.01, vs cisapride.
