Table 3.
Four h effect of prucalopride on intestinal motility in SD rats (-x ± s, n = 10)
Group | GI length (cm) | Migration of activated charcoal (cm) | GI propulsion rate (%) |
Control | 89.9 ± 8.6 | 78.0 ± 7.3 | 86.8 ± 2.6 |
Prucalopride (1 mg/kg) | 83.7 ± 5.1 | 76.3 ± 5.2 | 91.2 ± 2.2ad |
Prucalopride (2 mg/kg) | 97.4 ± 9.8 | 87.3 ± 10.4 | 91.3 ± 3.9ad |
Cisapride (1 mg/kg) | 99.5 ± 12.7 | 88.1 ± 13.7 | 88.6 ± 3.5 |
P < 0.05, vs cisapride;
P < 0.01, vs control.