Figure 1.

F56 inhibited the migration of HUVECs. A. HUVECs were treated with VEGF alone or in combination with F56 or scr F56 for 24, 48 and 72 hr. The proliferation of HUVECs was measured by CCK-8. B. The migration of HUVECs was measured by the transwell system. Representative images of migrated were shown (left) and the bar graph (right) showed the number of migrated cells. C. The migration of HUVECs was measured by the wound healing assay. Representative images of wound closure were shown (left) and the bar graph (right) showed the percentages of wound closure. Data are expressed as mean ± SEM. *P < 0.05.