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. 2015 Sep 15;5(10):3249–3259.

Table 2.

Clinical characteristics and their prediction of overall survival in 362 HCC patients receiving surgical resection for the tumor

Characteristics No of patients No of events 5-y-survival (%) Overall survival

MST (95% CI) Hazard ratio (95% CI) P
Number 362 225 30 34.0 (27.4-40.6)
Age (year)
    ≤50 186 113 30 35.0 (23.2-46.7) 1.000
    >50 176 112 29 33.0 (24.2-41.8) 1.098 (0.845-1.426) 0.483
Sex
    Female 63 41 27 31.0 (24.2-37.8) 1.000
    Male 299 184 30 37.0 (27.5-46.5) 0.885 (0.631-1.242) 0.481
Smoking
    Never 224 144 26 31.0 (23.2-38.8) 1.000
    Ever 138 81 37 39.0 (27.3-50.7) 0.858 (0.653-1.127) 0.270
Drinking
    Never 142 86 28 35.0 (19.6-50.4) 1.000
    Ever 220 139 31 33.0 (25.0-41.0) 1.071 (0.818-1.401) 0.619
Family history
    Absent 263 158 31 37.0 (27.3-46.7) 1.000
    Present 81 55 25 29.0 (17.4-40.6) 1.192 (0.877-1.620) 0.262
    Unknow 18 12
HbsAg
    Negative 59 40 35 22.0 (6.7-37.3) 1.000
    Positive 303 185 28 37.0 (30.2-43.8) 0.913 (0.648-1.287) 0.603
AFP
    Negative 142 95 26 33.0 (25.7-40.3) 1.000
    Positive 214 127 32 35.0 (26.1-43.9) 0.892 (0.684-1.164) 0.400
    Unknow 6 3
Tumor size (cm)
    ≤5 183 107 35 39.0 (28.1-49.9) 1.000
    >5 179 118 24 30.0 (21.0-39.0) 1.343 (1.033-1.747) 0.028
Differentiation
    I+II 196 122 28 37.0 (27.5-46.5) 1.000
    III+IV 155 96 32 34.0 (26.0-42.0) 0.926 (0.708-1.120) 0.572
    Unknow 11 7
Tumor capsule
    Absent 177 113 28 31.0 (22.7-39.3) 1.000
    Present 181 110 31 37.0 (26.1-47.9) 0.913 (0.702-1.188) 0.499
    Unknow 4 2
Venous invasion
    Absent 257 150 33 39.0 (29.3-48.7) 1.000
    Present 102 73 22 26.0 (20.1-31.9) 1.368 (1.033-1.811) 0.029
    Unknow 3 2
Cirrhosis
    Absent 121 79 30 27.0 (13.6-40.4) 1.000
    Present 239 145 30 36.0 (29.6-42.4) 0.949 (0.721-1.249) 0.708
    Unknow 2 1
Tumor number
    Solitary 279 172 30 34.0 (26.0-42.0) 1.000
    Multiple 83 53 27 35.0 (24.5-45.5) 1.061 (0.780-1.445) 0.704
pTNM stage
    I+II 309 188 31 37.0 (30.7-43.3) 1.000
    III+IV 39 27 24 22.0 (13.0-31.0) 1.280 (0.855-1.916) 0.231
    Unknow 14 10

Abbreviations: MST, median survival time; CI, confidence interval; AFP, α-fetoprotein.

P<0.05.