Table 2.
Characteristics | No of patients | No of events | 5-y-survival (%) | Overall survival | ||
---|---|---|---|---|---|---|
| ||||||
MST (95% CI) | Hazard ratio (95% CI) | P | ||||
Number | 362 | 225 | 30 | 34.0 (27.4-40.6) | ||
Age (year) | ||||||
≤50 | 186 | 113 | 30 | 35.0 (23.2-46.7) | 1.000 | |
>50 | 176 | 112 | 29 | 33.0 (24.2-41.8) | 1.098 (0.845-1.426) | 0.483 |
Sex | ||||||
Female | 63 | 41 | 27 | 31.0 (24.2-37.8) | 1.000 | |
Male | 299 | 184 | 30 | 37.0 (27.5-46.5) | 0.885 (0.631-1.242) | 0.481 |
Smoking | ||||||
Never | 224 | 144 | 26 | 31.0 (23.2-38.8) | 1.000 | |
Ever | 138 | 81 | 37 | 39.0 (27.3-50.7) | 0.858 (0.653-1.127) | 0.270 |
Drinking | ||||||
Never | 142 | 86 | 28 | 35.0 (19.6-50.4) | 1.000 | |
Ever | 220 | 139 | 31 | 33.0 (25.0-41.0) | 1.071 (0.818-1.401) | 0.619 |
Family history | ||||||
Absent | 263 | 158 | 31 | 37.0 (27.3-46.7) | 1.000 | |
Present | 81 | 55 | 25 | 29.0 (17.4-40.6) | 1.192 (0.877-1.620) | 0.262 |
Unknow | 18 | 12 | ||||
HbsAg | ||||||
Negative | 59 | 40 | 35 | 22.0 (6.7-37.3) | 1.000 | |
Positive | 303 | 185 | 28 | 37.0 (30.2-43.8) | 0.913 (0.648-1.287) | 0.603 |
AFP | ||||||
Negative | 142 | 95 | 26 | 33.0 (25.7-40.3) | 1.000 | |
Positive | 214 | 127 | 32 | 35.0 (26.1-43.9) | 0.892 (0.684-1.164) | 0.400 |
Unknow | 6 | 3 | ||||
Tumor size (cm) | ||||||
≤5 | 183 | 107 | 35 | 39.0 (28.1-49.9) | 1.000 | |
>5 | 179 | 118 | 24 | 30.0 (21.0-39.0) | 1.343 (1.033-1.747) | 0.028† |
Differentiation | ||||||
I+II | 196 | 122 | 28 | 37.0 (27.5-46.5) | 1.000 | |
III+IV | 155 | 96 | 32 | 34.0 (26.0-42.0) | 0.926 (0.708-1.120) | 0.572 |
Unknow | 11 | 7 | ||||
Tumor capsule | ||||||
Absent | 177 | 113 | 28 | 31.0 (22.7-39.3) | 1.000 | |
Present | 181 | 110 | 31 | 37.0 (26.1-47.9) | 0.913 (0.702-1.188) | 0.499 |
Unknow | 4 | 2 | ||||
Venous invasion | ||||||
Absent | 257 | 150 | 33 | 39.0 (29.3-48.7) | 1.000 | |
Present | 102 | 73 | 22 | 26.0 (20.1-31.9) | 1.368 (1.033-1.811) | 0.029† |
Unknow | 3 | 2 | ||||
Cirrhosis | ||||||
Absent | 121 | 79 | 30 | 27.0 (13.6-40.4) | 1.000 | |
Present | 239 | 145 | 30 | 36.0 (29.6-42.4) | 0.949 (0.721-1.249) | 0.708 |
Unknow | 2 | 1 | ||||
Tumor number | ||||||
Solitary | 279 | 172 | 30 | 34.0 (26.0-42.0) | 1.000 | |
Multiple | 83 | 53 | 27 | 35.0 (24.5-45.5) | 1.061 (0.780-1.445) | 0.704 |
pTNM stage | ||||||
I+II | 309 | 188 | 31 | 37.0 (30.7-43.3) | 1.000 | |
III+IV | 39 | 27 | 24 | 22.0 (13.0-31.0) | 1.280 (0.855-1.916) | 0.231 |
Unknow | 14 | 10 |
Abbreviations: MST, median survival time; CI, confidence interval; AFP, α-fetoprotein.
P<0.05.