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. 2015 Sep 15;5(10):3270–3275.

Table 3.

Adverse events of 62 Chinese patients with advanced NSCLC and 2nd-line chemotherapy of nintedanib

Adverse Events Grade 1 or 2 Grade 3 or 4

Number Percentage Number Percentage
Diarrhea 44 71.0% 6 9.8%
Nausea 26 43.5% 4 6.5%
Chest pain 17 27.4% 3 4.8%
Fatigue 10 16.1% 2 3.2%
Nausea 13 21.0% 2 3.2%
Asthenia 8 12.9% 0 0%
Pneumonia 9 14.5% 5 8.1%
Hypertension 13 21.0% 7 11.3%
Vomiting 7 11.3% 3 4.8%
Hyperglycaemia 8 12.9% 1 1.6%
Bleeding 6 9.7% 1 1.6%
Anemia 4 6.5% 2 3.2%
Heart failure 31 50.0% 12 19.4%