Table 1.

Pharmacokinetics parameters of FL118 in human tumor and mouse plasma following a single IV administration

Sample	T1/2 (hr)	Tmax (hr)	Cmax (ng/g, ml)	AUC (hr*ng/g)	AUC∞ (hr*ng/g)	AUC% Extrap (%)	Vz (g/kg) (ml/kg)	Cl (g/hr/kg) (ml/hr/kg)
FaDu	6.852	0.167	115	413	448	7.74	33052	3343
SW620	12.75	0.167	158	842	897	6.17	30742	1671
Plasma	1.788	0.167	43	82	104	21.7	36849	14287