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Inhibition of tumor-growth by B16F10-ESAT-6-gpi/IL-21 CD133+CD44+ CSC vaccine in mice. A. Images shows the tumor sizes stripped from the differently vaccine immunized mice 40 days after mice were challenged with B16F10 cells. B. The quantification analysis of tumor volumes. C. Tumor free mice challenged with B16F10 cells for 25 days. D. Tumor bearing mouse survival. *p<0.05, **p<0.01 and ***p<0.003; refer to the statistically significant differences as indicated.
