Figure 3.

Effect of HMGB1 downregulation on proliferation and invasion of gallbladder cancer cells. A. siRNA-induced downregulation of HMGB1 in GBC-SD, TGBC-1 and TGBC-2 cells. β-actin was applied as the loading control. B. Effect of HMGB1 downregulation on proliferation of GBC-SD, TGBC-1 and TGBC-2 cells. Data are expressed as fold change of the wild type control (Which is assumed as 1). C. Effect of HMGB1 downregulation on invasion of GBC-SD, TGBC-1 and TGBC-2 cells. Data are similarly expressed as aforementioned. The results are representative of at least three separate experiments and shown as mean ± s.d. *P<0.05; **P<0.01, compared to the wild type control.