Skip to main content
. 2015 Nov 17;17(10):767–775. doi: 10.1016/j.neo.2015.10.001

Figure 2.

Figure 2

Metabolic profiles of A-07 tissue samples. 3D PLS-DA score plot (A) and corresponding loading plot (B) of samples with and samples without hypoxic regions, 3D PLS-DA score plot (C) and corresponding loading plot (D) of samples from tumors that did and samples from tumors that did not develop lung metastases, and 3D PLS-DA score plot (E) and corresponding loading plot (F) of samples from tumors that did and samples from tumors that did not develop lymph node metastases. The loadings are colored according to their Variable Importance in Projection (VIP) scores. The samples containing hypoxic tissue were clearly separated from the non-hypoxic samples [PLS-DA classification accuracy: 71% (sensitivity: 62.5%; specificity: 81.3%)], whereas the samples from the tumors that developed lung metastases were not separated from the samples from the tumors that did not develop lung metastases, and the samples from the tumors that developed lymph node metastases were not separated from the samples from the tumors that did not develop lymph node metastases.