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The sensitivity of human ovarian carcinoma cells to WT TP53 reintroduction correlates with p53 status. RT-PCR was performed on lysates from human cell lines expressing different p53 proteins (ALST:WT, OVCA433:WT/E248K, SKOV3:null, OVCA420:R273H, and OVCAR3:R248Q) following transfection with WT TP53 for 24 hours (*P < .05, N = 3).
