Table 1A.
Frequency of Hot-Spot Mutations in Ovarian Tumors and H179R and C277F Mutations Which Occurred Less Frequently
| Mutation | Ovarian Cancer Frequency | Other Cancer Frequency | Ratio |
|---|---|---|---|
| R175H* | 3.90% | 3.65% | 1.07 |
| R273H* | 3.12% | 2.68% | 1.16 |
| Y220C* | 2.60% | 1.67% | 1.56 |
| R248Q | 2.60% | 3.26% | 0.80 |
| I195T* | 2.34% | 0.57% | 4.09 |
| R273C | 2.08% | 3.96% | 0.53 |
| V157F | 1.82% | 0.75% | 2.43 |
| R248W* | 1.82% | 2.02% | 0.90 |
| R282W | 1.56% | 2.33% | 0.67 |
| C176Y* | 1.56% | 0.48% | 3.22 |
| S241F* | 1.30% | 0.40% | 3.28 |
| Y163C | 1.30% | 0.66% | 1.97 |
| H193R* | 1.30% | 0.84% | 1.56 |
| G245D | 1.30% | 0.44% | 2.95 |
| H179R* | 0.78% | 1.01% | 0.77 |
| C277F* | 0.26% | 0.18% | 1.48 |