Table 7.

Brain response abnormalities in ALS compared to HCs at rest.

Region	MNI coordinate (x, y, z)	SDM-Z	P-values	Voxels	Clusters of breakdown (no. of voxels)	Jackknife sensitivity analysis
Hypoactivity in ALS patients with bulbar sign compared to HCs
Right precentral gyrus, BA 4	42, −20, 64	−1.478	0.001728892	41	R precentral gyurs (36)	4 out of 6
					R postcentral gyrus (5)
Left precentral gyrus, BA 6	−38, −14, 56	−1.337	0.003860295	42	L precentral gyurs (32)	4 out of 6
					L postcentral gyrus (10)

ALS, amyotrophic lateral sclerosis; BA, Brodmann; HC, healthy control; MNI, Montreal Neurological Institute; SDM, signed differential mapping.