Figure 1.

Schematic overview of a mammalian eye (a) and vitreous preparation process for SPT (b–e). (a) The vitreous humor of the mammalian eye mainly consists of collagen fibrils, as well as the GAGs HA and HS, both of which carry several negative charges. From fresh ovine eyes (b), the vitreous humor is carefully removed (c), and nanoparticles are injected into the vitreous (d). Trajectories characterizing the thermal motion of the nanoparticles in the vitreous humor (e) are obtained by optical microscopy. To see this figure in color, go online.