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. 2015 Nov 17;109(10):2171–2181. doi: 10.1016/j.bpj.2015.10.002

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Interspecies comparison of the diffusive mobility of polystyrene and liposome particles in vitreous. (a) Comparison of the mobile fraction (D_app > 10% of D_free) of carboxyl-terminated (COOH), PEGylated (PEG), and amine-terminated (NH₂) 200 nm polystyrene particles in bovine, porcine, and ovine vitreous humor. (b) Comparison of the mobile fractions (D_app > 10% of D_free) of DOPG, DOPC, and DOTAP 200 nm liposomes in bovine, porcine, and ovine vitreous humor. Several hundred particle trajectories were acquired per sample and then categorized into mobile and immobile fractions. The error bars denote the standard deviation for those fractions as obtained from at least three vitreous samples. Asterisks denote statistically significant differences (^∗∗p < 0.01; ^∗∗∗p < 0.001). To see this figure in color, go online.