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. 2015 Nov 17;109(10):2037–2050. doi: 10.1016/j.bpj.2015.09.031

Figure 3.

Figure 3

Simulation results using the four-state ventricular cardiac myocyte model (n = 50 simulations) (A) Ca2+ spark histograms for 1 s bins. Black solid circles show the experimental data from Prosser et al. (11). (B) Myoplasmic Ca2+ concentration ([Ca2+]i). (C) Network SR Ca2+ concentration ([Ca2+]NSR). The myocyte is stretched continuously from 10 to 20 s, displaying a transient increase in the Ca2+ spark rate. To see this figure in color, go online.