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. 2015 Nov 24;5:17122. doi: 10.1038/srep17122

Figure 6. CDK12 truncations show diminished activity against the RNA Pol II CTD.

Figure 6

Comparison of in vitro kinase activity against a GST-CTD substrate by various CDK12 complexes and CDK9/Cyclin T1 (FL denotes full length proteins). A representative autoradiograph detecting 32P-GST-CTD product is shown together with a graphic representation of 3 biological replicates of each phosphorylation reaction.