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Responders for defecation frequency (intention-to-treat (ITT) and per-protocol (PP) analysis). A responder was defined as a subject with a weekly defecation frequency above baseline for at least 50 % of the time – that is, for at least 2 of the 4-week treatment period; due to missing data, six subjects (0·5 %) could not be classified as responders or non-responders. CFU, colony-forming units; OR, OR for being a responder. * Number of subjects (% responders).
