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. 2015 Nov 24;5:16927. doi: 10.1038/srep16927

Table 4. Correlation of BSRTC categories with BRAFV600E mutation and final diagnosis.

BSRTC categories n (%) Surgery (%) BRAFV600Emutation (%) Malignant Malignant Rate(95% CI)
I (Nondiagnostic) 43 (19.5) 20 (46.5) 10 (23.3) 12 27.9 (13.3–43.7)
II (Benign) 38 (17.3) 12 (31.6) 3 (7.9) 3 7.9 (1.7–21.4)
III (AUS/FLUS) 33 (15.0) 21 (63.6) 14 (42.4) 15 45.5 (28.1–63.7)
IV (FN/SFN) 4 (1.8) 4 (100.0) 0 (0.0) 3 75.0 (19.4–99.4)
V (Suspicious for malignancy) 65 (29.5) 65 (100.0) 55 (84.6) 64 98.5 (91.7–100.0)
VI (Malignancy) 37 (16.8) 37 (100.0) 32 (86.5) 37 100.0 (90.5–100.0)

Abbreviations: AUS/FLUS, atypia of undetermined significance or follicular lesion of undetermined significance; FN/SFN, follicular neoplasm or suspicious for a follicular neoplasm; CI, confidence interval.