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. 2014 Mar 1;12(2):110–119. doi: 10.1089/adt.2013.552

Fig. 3.

Fig. 3.

Voltage and use dependence of Cav1.2 block by verapamil. (A) Examples of voltage protocols used for detection of use-dependent (two-pulse protocol; i) and voltage-dependent (preconditioning protocol; ii) effects of verapamil. (B) Representative current traces for the two-pulse (i) and preconditioning (ii) voltage protocols. (C) Dose–response curves for Cav1.2 inhibition by verapamil in the two-pulse (i) and preconditioning (ii) protocols.