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. 2015 Nov 24;5:17206. doi: 10.1038/srep17206

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Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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PC9 lung cancer cells were cultured for 1–4 ds after the indicated transfection and addition of 0.5 mM proline (Pro) or P5C. (a,c,d) The cell proliferation assays were performed at 1–4 ds after transfections. Representative data at 4 ds data were shown. (b) ATP production in PC9 cells was performed using luciferase-based assay. Data shown (mean ± S.E.M., n = 3) represent one of three independent experiments. P values were obtained by two-tailed Student’s t-test. ^***P < 0.001 compared with siNEG control group. ^#P < 0.05, ^###P < 0.001 compared with “+ Pro” or “+ P5C” group in the same knockdown group.