Table 2.
Association between total CD4+, CD8+ and Foxp3+CD4+ T cells and clinocopathological characteristics
| Median, (range) CD4+ T cells | P | Median, (range) CD8+ T cells | P | Median, (range) Foxp3+CD4+ T cells | P | |
|---|---|---|---|---|---|---|
| Gender: | ||||||
| Female | 164 (29–456) | NS | 195 (68–406) | NS | 43 (7–88) | NS |
| Male | 209 (27–538) | 244 (59–499) | 48 (6–92) | |||
| Smoking status: | ||||||
| Smokers | 116 (29–265) | <0.05 | 138 (59–332) | <0.05 | 11 (6–77) | NS |
| Non-smokers | 238 (27–538) | 264 (67–499) | 52 (6–92) | |||
| Histological NSCLC type: | ||||||
| Adenocarcinoma | 215.5 (116–538) | <0.05 <0.05* |
284.5 (134–405) | NS | 56.5 (11–88) | NS |
| Squamous cell carcinoma | 282.5 (119–522) | 268.5 (109–499) | 57 (16–92) | |||
| Other | 176.5 (116–417) | 288 (92–361) | 45 (13–73) | |||
| pT status | ||||||
| pT1a-2b | 232 (116–538) | NS | 251 (92–406) | NS | 57 (11–92) | NS |
| pT3-4 | 238 (116–474) | 268.5 (137–499) | 53 (16–90) | |||
| Lymph node status: | ||||||
| Negative (N0) | 234 (125–522) | NS | 239 (109–403) | NS | 57 (11–90) | NS |
| Positive (N1-N3) | 235 (116–538) | 270 (92–499) | 55 (13–92) | |||
| Diferenciation: | ||||||
| Poor | 253 (116–538) | NS | 257.5 (109–499) | NS | 56 (11–92) | NS |
| Other | 212 (116–504) | 253 (92–406) | 58 (13–88) | |||
| COPD: | ||||||
| Present | 222.5 (116–538) | NS | 273 (123–405) | NS | 56 (16–88) | NS |
| Absent | 282 (126–522) | 241.5 (92–499) | 56.5 (11–92) |
*P < 0.05, Mann–Whitney test for difference between adenocarcinoma and squamous cell carcinoma